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Japanese

Issues Concerning Histological Diagnosis of Esophageal Squamous Lesions by Biopsy Specimens Gen Watanabe 1 , Yoichi Ajioka 1 , Ken Nishikura 1 , Takashi Kato 1 1Division of Molecular and Diagnostic Pathology, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan Keyword: 生検診断 , 食道上皮内腫瘍 , 扁平上皮癌 , intraepithelial neoplasia , dysplasia pp.571-577
Published Date 2011/5/24
DOI https://doi.org/10.11477/mf.1403102215
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 We may have difficulties in making a diagnosis as to whether esophageal squamous epithelium taken by biopsy is intraepithelial neoplasia or not in cases where the biopsy specimen is tiny, the cutting face of the HE section is parallel to the mucosal surface, or the cutting face is tangent to papillae of the squamous epithelium. Biopsy specimens from different sites of a lesion could lead to different diagnosis because of the histologic heterogeneity of the lesion. Moreover, different philosophies of pathologists cause problems about nomenclature in the histologic diagnosis of esophageal squamous neoplasia. The same lesion could have different names including dysplasia(low grade, high grade), intraepithelial neoplasia(low grade, high grade), and carcinoma in situ. Clinicians and pathologists should have consensus about treatment policies based on the histologic diagnosis of squamous lesions.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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